BUY ALD-52 FOR SALE
BUY ALD-52 FOR SALE, 1-Acetyl-N,N-diethyllysergamide (also known as ALD-52, 1-Acetyl-LSD, 1A-LSD, 1A-LAD, and mistakenly as Orange Sunshine) is a lesser-known psychedelic substance of the lysergamide class that produces LSD-like psychedelic effects when administered. It’s structurally related to psychedelic lysergamides like LSD and 1P-LSD and is reported to produce largely indistinguishable effects.
ALD-52 was originally discovered by Albert Hofmann in his study of LSD analogs, but it did not enter mainstream awareness until the 1960s through Western youth counterculture. ALD-52 gained public notoriety when it was supposedly distributed as LSD in the 1960s under the now-famous name “Orange Sunshine.” This was later disproven.
In Entry 26 of his compendium TiHKAL, which discussed LSD, Shulgin touched briefly on the subject of ALD-52. His writings are vague second hand accounts saying doses in the 50–175 µg range have resulted in various conclusions. One account found that there was less visual distortion than with LSD and it seemed to produce less anxiety and tenseness and that it was somewhat less potent. Another informant claimed it was more effective in increasing blood pressure. Yet another informant could not tell them apart.
ALD-52, or 1-Acetyl-N,N-diethyllysergamide, is a semisynthethic molecule of the lysergamide chemical class. ALD-52 is a substituted derivative of lysergic acid. ALD-52’s structure contains four rings, a bicyclic hexahydroindole fused to a bicyclic quinoline group. This core structure of ALD-52 is an ergoline derivative, and has tryptamine and phenethylamine structures embedded within it. ALD-52 contains a N,N-diethylcarboxamide functional group bound to R8 of the chemical structure. It is additionally substituted at carbon 6 with a methyl group.
ALD-52 is homologous to 1P-LSD, which contains a propionyl group bound to CH3CO- instead of the acetyl group bound to the same location. It is unknown how these differences account for differences in the two compound’s activity.
Further information: Serotonergic psychedelic
ALD-52 likely acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from ALD-52’s efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
ALD-52, alongside with 1P-LSD, is believed to act as a prodrug to LSD, though it is unclear as to whether it is capable of exerting its own effects. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .